Microsoft has released Service Pack 4 (SP4) for Windows NT 4.0, incorporating all post-SP3 hotfixes plus patches for numerous bugs, including fixes for a number of security vulnerabilities.
You can obtain and install SP4 from http://www.microsoft.com/support/winnt/default.htm
As always, before installing the new service pack, be sure you have a clean backup in case you run into unexpected difficulties.
Note also that an excellent summary of post-SP4 hotfixes is available at http://www.conitech.com/windows/nt4sp4.html